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Takeda g protein coupled receptor tgr 5
G Protein Coupled Receptor Tgr 5, supplied by Takeda, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/g+protein+coupled+receptor+tgr+5/5+coupled+g+protein+receptor/pm41942011-311-15-14
Average 86 stars, based on 1 article reviews
g protein coupled receptor tgr 5 - by Bioz Stars, 2026-09
86/100 stars

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Article Title: The role of gut microbiota in neuropathic pain: insights into immune mechanisms
Article Snippet: 2) Takeda G protein-coupled receptor (TGR) −5, a G-protein coupled receptor widely expressed in the nervous system [ ], can be activated by bile acids, which then alleviates NP through TGR-5-dependent pathways [ ].

Article Title: The role of gut microbiota in neuropathic pain: insights into immune mechanisms.
Article Snippet: 2) Takeda G protein-coupled receptor (TGR) −5, a G-protein coupled receptor widely expressed in the nervous system [75], can be activated by bile acids, which then alleviates NP through TGR-5-dependent pathways [76].

Article Title: Gut-liver axis molecular mechanisms in alcohol-associated liver disease.
Article Snippet: Alcohol-associated liver disease (ALD) represents one of the most prevalent and devastating chronic liver diseases worldwide.. Yet, its pathogenesis and effective therapeutic strategies remain elusive.. The gut-liver axis, the bidirectional interaction between intestinal microbiota, microbial products, metabolites, bile acids, immune mediators, and the liver itself, has become a key focus in the study of ALD.

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Article Title: Treg conditioning endows activated Teff with suppressor function in juvenile autoimmune liver disease
Article Snippet: therapeutic alternatives.. Bile acid receptors (BAR) expressed on BEC present a promising target in the treatment of PBC due to their anticholestatic and anti-inflammatory properties.. However, little is known about how interactions between BEC and T cells may be regulated by BAR agonists.

Article Title: T cell interactions with the biliary epithelium in primary biliary cholangitis
Article Snippet: Background and Aims: BAs accumulation constitutes a devastating feature of cholestatic diseases.. Hepatic glucuronidation, catalyzed by the UGT1A3, 1A4, 2B4 and 2B7 enzymes, is viewed as a protective mechanism against BA toxicity.. The present study aimed at providing a comprehensive analysis of bile acid glucuronidation and its regulation by the bile acid sensors, FXR and PXR, in the context of cholestatic diseases.



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